Category: News (Page 1 of 10)

Announcing the 2025-2026 Biolocity Awardees: Pioneering Innovations in Biotechnology

Last month, Portal Innovations Atlanta generously hosted Biolocity for the 2025 Biolocity Social and Full Pitch Day. These events marked the culmination of months of dedicated effort by ten teams. On May 7th, each team presented their final pitch to the Biolocity team, the oversight committee, and interns. After a week of careful consideration, five teams were chosen.

 

What Lies Ahead for These Five Teams?

The chosen teams will benefit from a year of invaluable mentorship from Biolocity’s team, including the Entrepreneurs-In-Residence (EIRs), as well as non-dilutive funding to support their research and commercialization efforts. Let’s take a moment to meet our exceptional five grantees…


CytMesh | Georgia Tech and Emory University

Team: A. Fatih Sarioglu, Ph.D. & Tobey J. MacDonald, MD

Brain and central nervous system tumors are responsible for the highest morbidity and mortality rates not only among pediatric cancers but all other diseases of children. Clinicians are in critical need of a non-invasive assay capable of detecting minimal residual disease and sensitive in predicting future metastasis, treatment resistance, and disease progression, so that the clinician knows early on, before the disease has spread, that more effective therapy is needed. The CytMesh team has developed a lab test that can extract very rare and otherwise undetectable metastatic circulating tumor cells present in the bloodstream and cerebrospinal fluid samples of cancer patients so that their tumors can be non-invasively and serially monitored to better guide clinical decisions.


Infiltrate Bio | Georgia Tech

Team: Susan N. Thomas, Ph.D.

The Cell Adhesion Chromatography Project aims to develop a platform that predicts and enriches for immune cells with superior tumor-infiltrating potential. Led by Dr. Susan Thomas, this technology models the tumor vasculature to identify cell products most likely to traffic to solid tumors—a key bottleneck in adoptive cell therapies. By enabling the adhesion selection of cells, this platform supports improved efficacy, manufacturing processes, and clinical translation of cell therapies. This innovation stands to transform how immunotherapies are developed and deployed in cancer treatment.


Infinite Loupe | Emory

Team: Anthony Law MD, PhD and Atharva Madiwale, MS

Infinite Loupe is a mixed-reality surgical visualization system that combines optical zoom, 3D spatial awareness, and real-time digital augmentation in a wearable platform. Our goal is to replace the operative microscope with something more immersive, portable, and intelligent, helping surgeons see better, operate more precisely, and ultimately improve patient outcomes.


OnCuRNA – Drug Delivery for Solid Tumor Cancers | Georgia Tech

Team: Nick Housley, PhD, DPT, Alisyn Bourque, and M.G. Finn, Ph.D.

Ovarian cancer is the leading cause of death from gynecologic cancer among women. Unfortunately, existing systemic therapies have high toxicity and poor selectivity due to challenges in achieving high tumor delivery. To address this unmet need, the OnCuRNA team developed a new nanostructure (SANGs) that has shown great promise targeting and being retained in primary and metastatic ovarian cancer. This project focuses on realizing SANGs’ potential to improve chemotherapy delivery. The team will establish a versatile drug delivery platform and produce a library of SANG-drug combinations poised for advanced pharmaceutical development and commercialization.


RoboMateMR | Georgia Tech

Team: Yue Chen, Ph.D., Yifan Wang, Sam Wilcox, and Zhefeng Huang

RoboMateMR brings robotic precision to the MRI suite in an effort to improve the quality and access of cardiac MRI (CMR). CMR is an important tool in the diagnosis and monitoring of various heart diseases. Unfortunately, the quality and ability to perform effective CMR is threatened by the presence of cardiac implants, which produce artifacts that distort the image. RoboMateMR aims to enable the real-time correction of these artifacts through a robotically controlled shimming coil within the MRI scanner, enabling more effective treatment of cardiac conditions in patients with implants.


Biolocity is proud to support these visionary projects and their dedicated team members. These innovations exemplify our commitment to advancing biomedical technologies and improving healthcare outcomes. We look forward to the progress and breakthroughs these projects will undoubtedly achieve in the coming year. 

Stay tuned for more updates on these exciting projects and other Biolocity initiatives. Together, we continue to break boundaries in biotech and pave the way for a healthier future. 

Congratulations to all the 2025-2026 Biolocity awardees! 

 

Announcing the 2024-2025 Biolocity Awardees: Pioneering Innovations in Biotechnology


Biolocity is thrilled to announce the awardees for the 2024-2025 cycle, which recognizes groundbreaking innovations in biotechnology and medical research. This year, our awardees represent some of the most promising advancements in their respective fields, each with the potential to significantly impact healthcare and biomanufacturing.
 

Biolocity identifies projects through an annual, multi-stage application process designed to support university innovators with pitch coaching, market assessments, and competitive analysis, fostering commercial success. Throughout the application stages, faculty members collaborate with entrepreneur advisors to mitigate risks associated with their technology. An oversight committee comprising venture capitalists, entrepreneurs, clinicians, biomedical engineers, and university technology transfer experts makes the final selection of the cohort. 

This year’s cohort features: 

Bright QCEST Imaging
Principal Investigator: Phillips Sun, Ph.D. (Emory) 

Bright QCEST Imaging is at the forefront of molecular imaging, developing QCEST MRI technology to standardize and quantify molecular imaging. Dr. Phillips Sun’s project aims to revolutionize MR spectroscopy, offering unparalleled precision and reliability in diagnostic imaging. This innovation can potentially transform the landscape of medical diagnostics, enabling more accurate detection and monitoring of various diseases. 

Cytodit
Principal Investigator: A. Fatih Sariouglu, Ph.D. (Georgia Tech) 

Cytodit introduces an autonomous, cell analytical quality-control platform for biomanufacturing workflows. Under the guidance of Dr. A. Fatih Sariouglu, this technology promises to enhance the efficiency and accuracy of cell analysis in biomanufacturing processes. By automating quality control, Cytodit aims to ensure higher consistency and reliability in biomanufactured products, paving the way for advancements in regenerative medicine and cell therapy. 

MCATS for HIT
Principal Investigators: Khalid Salaita, Ph.D. and Roman Sniecinski, MD (Emory) 

MCATS for HIT represents a novel diagnostic test for heparin-induced thrombocytopenia (HIT), utilizing cellular traction forces. Dr. Khalid Salaita and Dr. Roman Sniecinski lead this innovative project, which seeks to simplify and improve the accuracy of HIT diagnostics. This test can be performed in any clinical lab, making it a valuable tool for widespread clinical use and ensuring timely and accurate diagnosis of HIT, a potentially life-threatening condition. 

Water Bear Bio
Principal Investigators: Jesse Waggoner, MD & David R. Myers, Ph.D. (Emory) 

Water Bear Bio is developing a unique solution for RNA and DNA extraction and ambient temperature storage. Led by Dr. Jesse Waggoner and Dr. David R. Myers, this project aims to simplify genetic material handling and preservation, crucial for research and clinical diagnostics. By enabling ambient temperature storage, Water Bear Bio could reduce costs and logistical challenges associated with cold storage, making genetic testing and research more accessible worldwide. 

Urearetics for HFpEF
Principal Investigators: John Calvert, Ph.D., Eric Otlund, Ph.D.,  & Yanhua Wang, Ph.D. (Emory) 

The Urearetics for HFpEF project focuses on developing a new treatment option for Heart Failure with preserved Ejection Fraction (HFpEF). This multi-disciplinary team, including Dr. John Calvert, Dr. Eric Otlund, Dr. Jeff Sands, Dr. Janet Klein, and Dr. Yanhua Wang, is pioneering the use of Urearetics to address this challenging and often treatment-resistant condition. Their work holds promise for improving the quality of life and outcomes for HFpEF patients. 

Biolocity is proud to support these visionary projects and their dedicated investigators. These innovations exemplify our commitment to advancing biomedical technologies and improving healthcare outcomes. We look forward to the progress and breakthroughs these projects will undoubtedly achieve in the coming year. 

Stay tuned for more updates on these exciting projects and other Biolocity initiatives. Together, we continue to break boundaries in biotech and pave the way for a healthier future. 

Congratulations to all the 2024-2025 Biolocity awardees! 

NephroDI Secures a Series A Investment

NephroDI Therapeutics

We congratulate our portfolio team, NephroDI Therapeutics, on their recent milestone! NephroDI Therapeutics has announced a significant Series A investment by Sound Bioventures to accelerate the development of NDI-5001, a groundbreaking potential first-in-class therapy for pediatric orphan kidney disease.

This new funding will be instrumental in taking NDI-5001 into and through clinical proof of concept in treating Congenital Nephrogenic Diabetes Insipidus (NDI). This devastating genetic condition affects individuals from birth, leading to life-altering challenges such as producing large volumes of dilute urine daily and requiring excessive water intake to prevent dehydration.

With this investment and a previously announced strategic corporate partnership, NephroDI is poised to advance NDI-5001, a proprietary small molecule AMPK activator, into the clinic later this year. NDI-5001 has already received Orphan Drug Designation and Rare Pediatric Disease designation, making it eligible for the Priority Review Voucher by the FDA’s Office of Orphan Products Development.

Learn more and read the full press release at https://nephrodi.com/news/.

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